A human doctor in-the-loop from any AI agent
Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.
Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.
Our doctors, on retainer
Appendix is a real practice of board-certified physicians you can reach through any AI agent you already use. Think of us as concierge primary care for the agent era.

Emergency Medicine

Primary Care

Primary Care

Emergency Medicine & Pediatrics
Get started
Add Appendix to the tools you already use
Copy the instructions below and paste them into ChatGPT, Claude, Gemini, or any AI conversation. Your AI will walk you through the clinical intake, then direct you to submit your letter.
How it works
Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.
Talk to your AI.
Describe your symptoms to Claude, ChatGPT, or any AI assistant. The AI helps you write a thorough clinical letter — asking about your history, allergies, and symptoms — with its intrinsic knowledge further informed by our medical knowledge base.
We check your letter.
Our API reviews your submission for completeness (not medical decisions). If anything's missing, your AI asks follow-up questions and resubmits. No personal information leaves your AI until you're ready.
Our doctors weigh in.
One of our board-certified physicians personally reviews your letter and writes back with their clinical assessment, personalized guidance, and a prescription if medically appropriate.
Use any AI you already have
We didn't build a chatbot because you already have the best one. Appendix works with the AI assistant you already trust — Claude Code, ChatGPT, Gemini, or anything that can follow instructions.
Doctors who work with your AI
Our physicians believe AI-assisted documentation leads to more thorough, more honest clinical conversations. They review your full letter — your symptoms, your history, what your AI told you — and write back with their professional assessment, guidance, and a prescription if appropriate.
Privacy first
Unlike other “health chatbots,” nothing reaches Appendix until you explicitly tell your agent to submit. Talk through your symptoms with your personal AI as long as you want. Your private conversation stays private, we see only your final submission.
Healthcare for your whole family
Add your whole family to your account and skip the waiting room whenever a health question comes up. Every submission gets a full physician response — a clinical assessment, personalized guidance, and a prescription as medically appropriate.
Join the practice
$99
/month
+$29/mo per additional family member
- ✓Our doctors on retainer, accessible through any AI agent
- ✓Personal response from our in-house physicians with every submission
- ✓Prescriptions included as clinically appropriate
- ✓E-prescription sent to any U.S. pharmacy
- ✓Add family members for $29/mo each — adults and kids as young as 6 months
- ✓Cancel anytime
Building with Appendix? Talk to us about integration pricing →
Prescriptions when you need them. Guidance always.
Not sure if your concern fits? Submit it anyway. Our physicians review every case and provide personalized clinical guidance — even if a prescription isn't the right answer.
This is a representative sample, not an exhaustive list. Inclusion of a condition or medication does not guarantee a prescription — medications listed may not be appropriate for every patient, and all prescriptions and medical decisions are at the discretion of the reviewing Appendix physician.