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Human doctor review and prescriptions,
from your AI app

Your AI writes a medical encounter summary, submits it through our API, and our in-house doctors review it and prescribe if appropriate.

POST /api/v1/prescribing/query200 OK
{
"chief_complaint": "Migraines",
"hpi": "48 year-old female with headaches...",
"pmh": "Migraines previously treated with...",
"medications": "Ibuprofen 400mg PRN",
"allergies": "NKDA",
"patient_email": "patient@example.com"
}
Response
{
"final_decision_ready": true,
"consent_url": "appendix.com/consent/a1b2...?token=xyz"
}
OAuth-Style Consent
S
A
SampleCo works with Appendix
for e-prescribing
+A board-certified physician reviews your request.
+You confirm exactly what is being submitted.
+Approved Rx are e-prescribed to your pharmacy.
Continue

Our doctors, via API

Appendix is a real practice of board-certified physicians. Think of us as direct primary care on-demand, for the AI agent era.

Studio portrait of Emergency Physician

Emergency Medicine Physician

Emergency Medicine

Studio portrait of Primary Care Physician

Primary Care Physician

Primary Care

Studio portrait of Primary Care Physician

Primary Care Physician

Primary Care

Studio portrait of Emergency Medicine and Pediatrics Physician

Emergency Medicine and Pediatrics Physician

Emergency Medicine & Pediatrics

How it works

Four steps from your app to a real prescription.

POST /prescribing/query
{
"chief_complaint": "Migraines",
"hpi": "48F, headaches...",
"allergies": "NKDA"
}
200 OK consent_url
1

Call the API

Send the clinical request and your user's contact info with your developer key. Our AI completeness gate tells you if anything's missing.

S
A
SampleCo works with Appendix
for e-prescribing
+A physician reviews your request.
+You confirm what is submitted.
+Approved Rx are e-prescribed to your pharmacy.
Continue
2

Show the consent modal

We return a consent URL. Your user reviews exactly what's being submitted, attests to its accuracy, and consents to care with Appendix.

Verified
3

Identity

A one-time identity check via Stripe Identity. No identifying information is passed back to your app.

9:41
Appendixnow

Your prescription is approved.

4

A physician decides

A board-certified doctor reviews and prescribes if appropriate. The Rx is e-prescribed directly to the user's pharmacy of choice.

Built for healthcare builders

OAuth-style consent

A slim, brandable modal forms the patient-physician relationship directly with Appendix, structurally similar to Sign in with Google.

Instant sandbox

Test keys are issued the moment you sign up. Exercise the full integration: completeness gate, consent link, and simulated decision.

Usage-based, not enterprise

Pay per physician review from a prepaid balance. No contract, no minimums, no sales call. Simple to model and pass through to your users.

Identity, handled

Stripe Identity verifies your user once, built-in to the Appendix onboarding flow, and included in your cost.

Compliance built in

Appendix keeps consent, identity, indication limits, and physician review inside one controlled flow.

Two-way communication

Physician replies reach your user by email, or via integration with your app and our chat API.

Prescriptions when you need them. Guidance always.

Not sure if your concern fits? Submit it anyway. Our physicians review every case and provide personalized clinical guidance — even if a prescription isn't the right answer.

This is a representative sample, not an exhaustive list. Inclusion of a condition or medication does not guarantee a prescription — medications listed may not be appropriate for every patient, and all prescriptions and medical decisions are at the discretion of the reviewing Appendix physician.

Not building an app?

Appendix runs its own membership for individuals and families on this same platform — talk to the AI assistant you already use, and our doctors take it from there.

Your AI can write the visit.
Appendix brings the doctor.

Appendix

The prescribing layer for your AI

1800 JFK Blvd #300-91200
Philadelphia, PA 19103

© 2026 Appendix, Inc.

Stay in the loop

Occasional updates from the Appendix team.

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Appendix is for non-urgent medical concerns only. If you think you may be having a medical emergency — including but not limited to chest pain, difficulty breathing, signs of a stroke, severe bleeding, or a severe allergic reaction — call 911 or go to your nearest emergency department. Do not wait for a response from Appendix. Appendix is not for mental health crises. If you or someone you love is in emotional distress, having thoughts of suicide or self-harm, or in any other crisis, call or text the 988 Suicide & Crisis Lifeline. Appendix is not a triage or diagnostic tool and should not be used as one. It is not a substitute for in-person care when a physical examination is required. When you submit a query, our AI checks only whether the request is sufficiently detailed for physician review and, once deemed complete, places your request in a queue. Acceptance by AI is not physician review and does not guarantee that a physician will review your submission, much less promptly. Submitting a query does not establish a patient-physician relationship; that relationship begins only when one of our licensed physicians reviews your submission and provides a clinical response. AI assists with documentation only. All clinical decisions are made by our board-certified physicians. By accessing medical services through the Appendix platform, you are responsible for the content of any submission made on your behalf — including submissions made by an AI agent acting under your direction. Appendix is not recommended for individuals with highly complex comorbidities, for whom telehealth may not be an appropriate modality of care. Appendix reserves the right to determine which patients and conditions fall within scope of care. By accessing our site or our services — including the API, agent skills, and Model Context Protocol (MCP) server — you agree to our Terms of Service (https://appendix.com/terms-of-service) and Privacy Policy (https://appendix.com/privacy-policy).