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A human doctor in-the-loop from any AI agent

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

claude code
I've gathered enough details about your migraines to build the encounter summary. Submitting to Appendix now.
POST appendix.com/api/v1/agent/query
200 OK
Your encounter summary has been submitted and is ready for physician review. Complete checkout to pay and choose your pharmacy:
appendix.com/checkout/a1b2c3
>

Our doctors, on retainer

Appendix is a real practice of board-certified physicians you can reach through any AI agent you already use. Think of us as concierge primary care for the agent era.

Studio portrait of Emergency Physician

Emergency Medicine Physician

Emergency Medicine

Studio portrait of Primary Care Physician

Primary Care Physician

Primary Care

Studio portrait of Primary Care Physician

Primary Care Physician

Primary Care

Studio portrait of Emergency Medicine and Pediatrics Physician

Emergency Medicine and Pediatrics Physician

Emergency Medicine & Pediatrics

Get started

Add Appendix to the tools you already use

Copy the instructions below and paste them into ChatGPT, Claude, Gemini, or any AI conversation. Your AI will walk you through the clinical intake, then direct you to submit your letter.

Loading instructions...

How it works

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

1

Talk to your AI.

Describe your symptoms to Claude, ChatGPT, or any AI assistant. The AI helps you write a thorough clinical letter — asking about your history, allergies, and symptoms — with its intrinsic knowledge further informed by our medical knowledge base.

2

We check your letter.

Our API reviews your submission for completeness (not medical decisions). If anything's missing, your AI asks follow-up questions and resubmits. No personal information leaves your AI until you're ready.

3

Our doctors weigh in.

One of our board-certified physicians personally reviews your letter and writes back with their clinical assessment, personalized guidance, and a prescription if medically appropriate.

claude
> /appendix I think I have a UTI, do I need an antibiotic?
> /appendix swollen calf after a long flight — DVT? can you order an ultrasound for me?
> /appendix can I drink wine while I'm on metronidazole?
>

Use any AI you already have

We didn't build a chatbot because you already have the best one. Appendix works with the AI assistant you already trust — Claude Code, ChatGPT, Gemini, or anything that can follow instructions.

Doctors who work with your AI

Our physicians believe AI-assisted documentation leads to more thorough, more honest clinical conversations. They review your full letter — your symptoms, your history, what your AI told you — and write back with their professional assessment, guidance, and a prescription if appropriate.

claude
> /appendix my ENT wants to do sinus surgery — second opinion?
> /appendix here's my MRI report, help me understand what 'mild disc bulge L4-L5' means
> /appendix my CGM shows post-meal spikes to 160, should I be worried?
>
claude
> I want to think through this before sharing with anyone
> ask me questions, but don't send anything yet
> ok I'm ready — /appendix submit this letter for review
>

Privacy first

Unlike other “health chatbots,” nothing reaches Appendix until you explicitly tell your agent to submit. Talk through your symptoms with your personal AI as long as you want. Your private conversation stays private, we see only your final submission.

Healthcare for your whole family

Add your whole family to your account and skip the waiting room whenever a health question comes up. Every submission gets a full physician response — a clinical assessment, personalized guidance, and a prescription as medically appropriate.

claude
> /appendix my 8-month-old has a fever and won't eat, what should I do?
> /appendix my mom seems confused this week — UTI, delirium, or something worse?
> /appendix kid fell off the trampoline, wrist is swollen — ER or watch overnight?
>

Join the practice

$99

/month

+$29/mo per additional family member

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  • Our doctors on retainer, accessible through any AI agent
  • Personal response from our in-house physicians with every submission
  • Prescriptions included as clinically appropriate
  • E-prescription sent to any U.S. pharmacy
  • Add family members for $29/mo each — adults and kids as young as 6 months
  • Cancel anytime

Building with Appendix? Talk to us about integration pricing →

Prescriptions when you need them. Guidance always.

Not sure if your concern fits? Submit it anyway. Our physicians review every case and provide personalized clinical guidance — even if a prescription isn't the right answer.

This is a representative sample, not an exhaustive list. Inclusion of a condition or medication does not guarantee a prescription — medications listed may not be appropriate for every patient, and all prescriptions and medical decisions are at the discretion of the reviewing Appendix physician.

Your AI can write the visit.
Appendix brings the doctor.